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Updated: Jan 5, 2026

Applying Advanced In Vitro Culturing Technology to Study the Human Gut Microbiota
Published on: February 15, 2019
Systems biology perspective for studying the gut microbiota in human physiology and liver diseases
Ozlem Altay1, Jens Nielsen2, Mathias Uhlen1
1Science for Life Laboratory, KTH - Royal Institute of Technology, Stockholm, Sweden.
Abstract:
The advancement in high-throughput sequencing technologies and systems biology approaches have revolutionized our understanding of biological systems and opened a new path to investigate unacknowledged biological phenomena. In parallel, the field of human microbiome research has greatly evolved and the relative contribution of the gut microbiome to health and disease have been systematically explored. This review provides an overview of the network-based and translational systems biology-based studies focusing on the function and composition of gut microbiota. We also discussed the association between the gut microbiome and the overall human physiology, as well as hepatic diseases and other metabolic disorders.
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