Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Predictors and clinical course of chronic limb-threatening ischemia with hemodynamic failure after endovascular therapy.

Vascular medicine (London, England)·2026

Same author

Internal Endoconduit-Assisted Transfemoral TAVR in a Patient With Severely Diseased Iliofemoral Anatomy.

JACC. Case reports·2026

Same author

Evaluating the Precision of Intra-Spline Bipolar Potentials With Pentaspline Pulsed Field Ablation Catheter.

Journal of arrhythmia·2026

Same author

Pathological Insights Into the Relationship Between Medial and Intimal Calcification in Lower Extremity Artery Disease.

JACC. Advances·2026

Same author

Prognostic Impact of Lower Extremity Arterial Disease Compared with Coronary Artery Disease After Revascularisation in Patients Receiving Haemodialysis: A Subanalysis of the ASPARAGUS Registry.

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery·2026

Same author

Lipoprotein(a) and Peripheral Artery Disease as Independent Predictors of Arterial Stiffness in Patients With Hypertension: A Single-Center Cross-Sectional Study.

Journal of clinical hypertension (Greenwich, Conn.)·2026

Search research articles

Related Experiment Video

Updated: Jan 5, 2026

Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound

Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound

Published on: April 21, 2023

Is Angiosome-Guided Endovascular Therapy Worthwhile?

Yosuke Hata¹, Osamu Iida¹, Toshiaki Mano¹

¹Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Hyogo, Japan.

Annals of Vascular Diseases

|October 23, 2019

Summary

Angiosome-guided endovascular therapy (EVT) for critical limb ischemia (CLI) shows promise for wound healing, though its impact on survival needs further investigation. Future research should focus on patient and lesion factors influencing wound healing outcomes.

Keywords:

angiosome concept critical limb ischemia endovascular therapy wound care

More Related Videos

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

Simulator Training for Endovascular Neurosurgery

Simulator Training for Endovascular Neurosurgery

Published on: May 6, 2020

Related Experiment Videos

Last Updated: Jan 5, 2026

Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound

Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound

Published on: April 21, 2023

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

Simulator Training for Endovascular Neurosurgery

Simulator Training for Endovascular Neurosurgery

Published on: May 6, 2020

Area of Science:

Vascular Surgery
Interventional Cardiology
Peripheral Artery Disease

Background:

Endovascular therapy (EVT) is crucial for treating critical limb ischemia (CLI).
Current guidelines recommend considering the angiosome concept for infrapopliteal revascularization in CLI patients.
Existing literature presents mixed results regarding angiosome-guided EVT.

Purpose of the Study:

To evaluate the effectiveness of angiosome-guided EVT in CLI treatment.
To compare wound healing (WH) and survival outcomes of angiosome-guided EVT.
To explore the potential of indirect revascularization within the angiosome concept.

Main Methods:

Review of previous reports on angiosome-guided EVT for CLI.
Analysis of wound healing, amputation-free survival, and overall survival data.
Comparison of direct versus indirect revascularization outcomes based on the angiosome concept.

Main Results:

Angiosome-guided EVT appears to favor wound healing over survival benefits.
Indirect revascularization, guided by the angiosome concept and good collaterals, may yield comparable wound healing to direct revascularization.
The overall impact on amputation-free and overall survival requires further clarification.

Conclusions:

While angiosome-guided EVT shows potential for improving wound healing in CLI, its effect on survival remains less clear.
Indirect revascularization within the angiosome framework can be effective for wound healing.
Future research should identify patient and lesion characteristics influencing wound healing after angiosome-guided EVT for optimized clinical application.