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Related Concept Videos

Empirical Method to Interpret Standard Deviation01:09

Empirical Method to Interpret Standard Deviation

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The empirical rule, also known as the three-sigma rule, allows a statistician to interpret the standard deviation in a normally distributed dataset. The rule states that 68% of the data lies within one standard deviation from the mean, 95% lies within two standard deviations from the mean, and 99.7% lies within three standard deviations from the mean. Additionally, this rule is also called the 68-95-99.7 rule.
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Method validation is a crucial process in analytical chemistry designed to confirm that a given method consistently produces reliable and high-quality results. This process is essential when a method is applied to different sample matrices or when procedural modifications are made, ensuring that the results meet acceptable standards across various applications.
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A physical quantity is defined either by specifying its measurement method or by stating how it is calculated from other measurements. For example, consider a metallic cube. We might define its mass and dimensions by specifying methods for measuring them, such as using a weighing machine and a meter scale. Then, we could define the volume by stating that it is the cube of its side, and we could calculate the density as the mass divided by the volume.
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Standard solutions refer to solutions with a precisely known concentration or composition. A primary standard is a highly pure, high molar mass, stable substance that is entirely soluble in water, the most commonly used solvent in analytical chemistry. The primary standard solution can be used to standardize secondary standards, which are substances with known concentrations but are less pure and stable. Standard solutions are essential for achieving accurate and reliable results in analytical...
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Author Spotlight: Biological Standardization to Ensure Reproducibility and Harmonization in Research
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Methodology and timing of standardization.

Luca Bertolaccini1, Gaetano Rocco2

  • 1Department of Thoracic Surgery, Maggiore Teaching Hospital, Bologna, Italy.

Journal of Thoracic Disease
|October 23, 2019
PubMed
Summary
This summary is machine-generated.

Uniportal VATS (video-assisted thoracoscopic surgery) offers a minimally invasive approach for lung resections, providing reduced morbidity and faster recovery. This consensus statement refines its indications and techniques for thoracic surgeons.

Keywords:
Delphi techniqueUniportal VATSlung cancermethodology

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Area of Science:

  • Thoracic Surgery
  • Minimally Invasive Surgery
  • Pulmonary Medicine

Background:

  • Uniportal VATS has emerged as a revolutionary technique for major lung resections over the past decade.
  • It offers a balance between reduced patient morbidity and enhanced postoperative recovery.
  • Outcomes in terms of morbidity, mortality, and oncologic value are comparable to traditional open thoracotomy and multi-port VATS.

Purpose of the Study:

  • To establish a consensus statement on the indications and techniques for uniportal VATS.
  • To define best practices for uniportal VATS lobectomy through expert consensus.
  • To optimize perioperative management and training for uniportal VATS procedures.

Main Methods:

  • A Delphi process involving international experts in uniportal VATS was employed.
  • Three rounds of voting were conducted to achieve consensus.
  • Key features included participant anonymity, iterative feedback, and controlled information dissemination.

Main Results:

  • A consensus statement was developed regarding the indications and techniques for uniportal VATS.
  • The Delphi process successfully defined optimal procedures, perioperative management, and training strategies.
  • Expert agreement was reached on the application of uniportal VATS for various intrathoracic conditions.

Conclusions:

  • Uniportal VATS is a validated and effective approach for major lung resections.
  • The consensus statement provides a framework for standardized and optimized uniportal VATS procedures.
  • Further adoption and refinement of uniportal VATS are supported by this expert consensus.