Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

915
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
915
Glaucoma: Overview01:25

Glaucoma: Overview

1.2K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.2K
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.1K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Partner change, birth interval and risk of pre-eclampsia: a paradoxical triangle.

Paediatric and perinatal epidemiology·2007
Same author

Partner change and perinatal outcomes: a systematic review.

Paediatric and perinatal epidemiology·2007
Same author

A controversial tumor marker: is SM22 a proper biomarker for gastric cancer cells?

Journal of proteome research·2007
Same author

A strategy for high-throughput analysis of levosimendan and its metabolites in human plasma samples using sequential negative and positive ionization liquid chromatography/tandem mass spectrometric detection.

Rapid communications in mass spectrometry : RCM·2007
Same author

[Leukemic cell apoptosis induced by anti-human DR5 monoclonal antibody mDRA-6].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology·2007
Same author

[Infection of intervertebral space and the interventional therapy].

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences·2007

Related Experiment Video

Updated: Jan 5, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

1.8K

Progression on canaloplasty for primary open angle glaucoma.

Jun Zhang1,2, Ning-Li Wang1

  • 1Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100005, China.

International Journal of Ophthalmology
|October 23, 2019
PubMed
Summary

Ab interno canaloplasty (ABiC) is a minimally invasive glaucoma surgery that reconstructs natural fluid outflow to effectively lower eye pressure. This no-bleb procedure offers high efficiency and security for glaucoma patients.

Keywords:
ab-interno canaloplastycanaloplastyglaucoma

More Related Videos

Ultrasound Cyclo Plasty in Eyes with Glaucoma
05:05

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

12.6K
Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

1.7K

Related Experiment Videos

Last Updated: Jan 5, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

1.8K
Ultrasound Cyclo Plasty in Eyes with Glaucoma
05:05

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

12.6K
Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

1.7K

Area of Science:

  • Ophthalmology
  • Surgical Innovation
  • Glaucoma Research

Background:

  • Glaucoma is a leading cause of irreversible blindness.
  • Non-penetrating glaucoma surgery (NPGS) aims to improve aqueous humor outflow.
  • Traditional canaloplasty dilates Schlemm's canal to enhance physiological outflow.

Purpose of the Study:

  • To introduce Ab interno canaloplasty (ABiC) as an advanced MIGS procedure.
  • To evaluate ABiC's efficacy in reconstructing natural aqueous humor outflow pathways.
  • To assess the safety and effectiveness of ABiC in mild-to-moderate primary open angle glaucoma (POAG) patients.

Main Methods:

  • ABiC is a minimally invasive glaucoma surgery (MIGS) technique.
  • It reconstructs the natural outflow pathways by dilating Schlemm's canal.
  • This procedure is a refinement of traditional canaloplasty.

Main Results:

  • ABiC demonstrates high efficiency in reducing intraocular pressure (IOP).
  • The procedure offers a high security profile for patients.
  • No complications such as scar formation or encapsulation were reported, as it is a no-bleb surgery.

Conclusions:

  • ABiC is an effective and secure MIGS for managing POAG.
  • It successfully reconstructs physiological aqueous humor outflow.
  • The no-bleb nature of ABiC avoids common NPGS complications.