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Correlation between obstructive sleep apnea and central retinal vein occlusion.
Yan-Hui Wang1, Peng Zhang2, Lian Chen2
1Department of Otolaryngology, Xi'an No.3 Hospital, the Affiliated Hospital of Northwest University, Xi'an 710018, Shaanxi Province, China.
International Journal of Ophthalmology
|October 23, 2019
Summary
Obstructive sleep apnea (OSA) is linked to central retinal vein occlusion (CRVO). Patients with CRVO showed higher apnea-hypopnea index (AHI) and oxygen desaturation index (ODI) suggesting OSA may be a risk factor.
Area of Science:
- Ophthalmology
- Sleep Medicine
- Cardiovascular Research
Background:
- Central retinal vein occlusion (CRVO) is a significant cause of vision loss.
- Obstructive sleep apnea (OSA) is a common sleep disorder associated with cardiovascular complications.
Purpose of the Study:
- To investigate the potential correlation between obstructive sleep apnea (OSA) and central retinal vein occlusion (CRVO).
Main Methods:
- Thirty CRVO patients and 30 age/sex-matched controls underwent polysomnography.
- Apnea-hypopnea index (AHI) and oxygen desaturation index (ODI) were measured.
- Correlation analysis with BMI was performed.
Main Results:
- CRVO patients exhibited significantly higher AHI and ODI compared to controls (P=0.008 and P=0.001).
- OSA prevalence was significantly higher in CRVO patients (73.33%) than controls (40.00%; P=0.019).
- AHI positively correlated with BMI and ODI in both groups.
Conclusions:
- Obstructive sleep apnea may serve as a risk factor or trigger for the development of CRVO.
- Findings suggest a link between sleep-disordered breathing and retinal vascular events.
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