Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Narcolepsy01:07

Narcolepsy

453
Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
453
REM Sleep Behavior Disorder01:15

REM Sleep Behavior Disorder

1.2K
REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
1.2K
Sleep-Wake Cycles01:24

Sleep-Wake Cycles

2.6K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
2.6K
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

352
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
352
Sleep Apnea01:21

Sleep Apnea

430
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
430
Restless Leg Syndrome and Night Terrors01:27

Restless Leg Syndrome and Night Terrors

442
Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
442

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Elevated sclerostin levels in cerebrospinal fluid are associated with cognitive impairment in the Alzheimer's disease continuum.

Alzheimer's & dementia (Amsterdam, Netherlands)·2026
Same author

Neuropsychological, biological, and electrophysiological outcomes of gamma-tACS in MCI-AD: A case series.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2026
Same author

Virtual brain and electroencephalography explain the variance of memory alterations in mild cognitive impairment.

Alzheimer's research & therapy·2026
Same author

Anti-CGRP monoclonal antibody therapy for migraine is not associated with early adverse bone effects: a prospective, observational, controlled, cohort study.

Frontiers in neurology·2026
Same author

Whole anterior visual pathway segmentation from high-resolution MRI using artificial intelligence.

European radiology experimental·2026
Same author

Incidence of Dementia With Lewy Bodies in Salento, Italy: A Population-Based Study.

Neurology·2026

Related Experiment Video

Updated: Jan 5, 2026

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
04:33

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

1.2K

Framing multiple sclerosis under a polysomnographic perspective.

Kosuke Tanioka1,2, Anna Castelnovo2,3, Naoko Tachibana4

  • 1Department of Neurology, Osaka City General Hospital, Osaka, Japan.

Sleep
|October 23, 2019
PubMed
Summary

Sleep disorders are common in multiple sclerosis (MS), but objective data are scarce. This review examines polysomnography findings and their clinical links in MS patients, highlighting the need for more research.

Keywords:
AHIPLMPSGRLSapneasmultiple sclerosisperiodic leg movementsrestless leg syndromesleepsleep architecture

More Related Videos

Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood
08:20

Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood

Published on: October 2, 2019

12.4K
Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice
10:56

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

Published on: August 2, 2017

10.4K

Related Experiment Videos

Last Updated: Jan 5, 2026

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
04:33

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

1.2K
Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood
08:20

Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood

Published on: October 2, 2019

12.4K
Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice
10:56

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

Published on: August 2, 2017

10.4K

Area of Science:

  • Neurology
  • Sleep Medicine
  • Autoimmune Diseases

Background:

  • Multiple sclerosis (MS) is a disabling autoimmune neurological disease.
  • MS presents with evident motor symptoms and less recognized symptoms impacting quality of life.
  • Sleep disturbances are increasingly recognized as significant but understudied MS comorbidities.

Purpose of the Study:

  • To systematically review objective sleep findings in MS patients using polysomnography.
  • To explore the relationship between objective sleep data and clinical variables in MS.
  • To identify gaps in current objective research on sleep disorders in MS.

Main Methods:

  • Systematic literature review.
  • Analysis of studies utilizing polysomnography to assess sleep in MS patients.
  • Correlation of polysomnographic data with clinical MS characteristics.

Main Results:

  • Subjective reports indicate high frequency of sleep disorders in MS.
  • Objective polysomnography data on sleep disturbances in MS remain limited.
  • The relationship between objective sleep findings and clinical MS variables requires further investigation.

Conclusions:

  • While subjective reports suggest frequent sleep disorders in MS, objective data are scarce.
  • There is a critical need for large-scale, objective instrumental investigations.
  • Further research is warranted to define the objective nature and clinical impact of sleep comorbidities in MS.