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Updated: Jan 5, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
New diterpenoids from the rhizomes of Hedychium forrestii
Wen-Hui Wang1, Jie-Jie Gao1, Xiao-Fei Zuo1
1School of Chinese Materia Medica, Yunnan University of Chinese Medicine, Kunming, People's Republic of China.
Abstract:
A novel hexanorditerpenoid, hedychin C (1), and a new diterpenoid, hedychin D (2), were isolated from the rhizomes of Hedychium forrestii. Their structures and absolute configurations were unambiguously established by means of extensive spectroscopic data (IR, UV, HRMS, and NMR) and electronic circular dichroism (ECD) calculations. This is the first report of naturally occurring labdane-type hexanorditerpenoid. Compound 1 was proved to have moderate cytotoxicity against XWLC-05 cell line with an IC50 value of 53.6 μM.
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