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Related Experiment Video

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Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
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Allergen immunotherapy in asthma: current evidence.

Plamena Novakova1, Angelica Tiotiu2,3,4, Ilaria Baiardini5

  • 1Clinic of Clinical Allergy, Medical University Sofia, Sofia, Bulgaria.

The Journal of Asthma : Official Journal of the Association for the Care of Asthma
|October 23, 2019
PubMed
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Allergen immunotherapy shows promise for mild to moderate allergic asthma, particularly for house dust mite and pollen sensitivities. Further research is needed for severe cases and other allergens.

Keywords:
Allergyquality of liferecommendationssensitizationtreatment

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Area of Science:

  • Allergy and Immunology
  • Respiratory Medicine

Background:

  • Allergic asthma is a common clinical condition.
  • Allergen immunotherapy offers specific, long-term allergy treatment.
  • Current use of allergen immunotherapy in asthma is suboptimal.

Purpose of the Study:

  • To review evidence on allergen immunotherapy's impact on allergic asthma.
  • To assess effects on clinical outcomes and quality of life.
  • To focus on common allergen extracts.

Main Methods:

  • Systematic review of randomized controlled trials and meta-analyses.
  • Searched databases: PubMed, Scopus, Web of Science (2002-2019).
  • Keywords included 'allergen immunotherapy,' 'asthma,' and specific allergens (mites, pollens, molds, pets).

Main Results:

  • Allergen immunotherapy positively impacts outcomes in mild to moderate asthma patients sensitized to house dust mites and pollens.
  • Emerging data supports its inclusion as a therapeutic option.
  • Limited data exists for mold/pet sensitization and severe allergic asthma.

Conclusions:

  • Allergen immunotherapy is a potential treatment for select allergic asthma patients.
  • More research is required on optimal treatment duration and severe asthma.
  • Cost-effectiveness and role in severe asthma need further investigation.