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Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
The radiological diagnosis of pneumonia in children
Kerry-Ann F O'Grady1, Paul J Torzillo2,3, Kieran Frawley4
116Queensland Children's Medical Research Institute, Queensland University of Technology, Level 4, Foundation Building, Herston, Queensland Australia.
Insights
Diagnosing pediatric pneumonia lacks a definitive standard. Radiology, including chest X-rays, is useful but has limitations, especially in distinguishing infection types and in routine clinical use.
Area of Science:
- Pediatric Pulmonology
- Diagnostic Imaging
- Infectious Diseases
Background:
- Paediatric pneumonia is a significant global cause of child morbidity and mortality.
- Current diagnostic methods, including clinical, microbiological, and radiological approaches, have variable utility and limitations.
- A definitive gold standard for diagnosing pediatric pneumonia is still lacking.
Purpose of the Study:
- To review the role and limitations of radiology in diagnosing paediatric pneumonia.
- To evaluate the utility of various radiological modalities in different clinical settings.
- To identify knowledge gaps and future research needs in radiological pneumonia diagnosis.
Main Methods:
- Review of existing literature on radiological diagnosis of paediatric pneumonia.
- Analysis of the application and limitations of chest radiography (CXR), computed tomography (CT), ultrasonography, and magnetic resonance imaging (MRI).
- Discussion of diagnostic challenges in various healthcare settings.
Main Results:
- Chest radiographs (CXRs) are widely used but not indicated for ambulatory settings and cannot differentiate viral from bacterial infections.
- Standardized CXR definitions for epidemiological studies are not directly applicable to clinical practice.
- Advanced imaging like CT, ultrasonography, and MRI are valuable for complicated pneumonias but not for routine diagnosis.
Conclusions:
- Radiology plays a role in paediatric pneumonia diagnosis, particularly in complicated cases, but limitations exist for routine use.
- Further large-scale, population-based studies are required to address knowledge gaps in radiological diagnosis.
- The feasibility of conducting such extensive studies remains a significant barrier.
Abstract:
Despite the importance of paediatric pneumonia as a cause of short and long-term morbidity and mortality worldwide, a reliable gold standard for its diagnosis remains elusive. The utility of clinical, microbiological and radiological diagnostic approaches varies widely within and between populations and is heavily dependent on the expertise and resources available in various settings. Here we review the role of radiology in the diagnosis of paediatric pneumonia. Chest radiographs (CXRs) are the most widely employed test, however, they are not indicated in ambulatory settings, cannot distinguish between viral and bacterial infections and have a limited role in the ongoing management of disease. A standardised definition of alveolar pneumonia on a CXR exists for epidemiological studies targeting bacterial pneumonias but it should not be extrapolated to clinical settings. Radiography, computed tomography and to a lesser extent ultrasonography and magnetic resonance imaging play an important role in complicated pneumonias but there are limitations that preclude their use as routine diagnostic tools. Large population-based studies are needed in different populations to address many of the knowledge gaps in the radiological diagnosis of pneumonia in children, however, the feasibility of such studies is an important barrier.
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