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Sleep apnea in olivopontocerebellar degeneration: treatment with trazodone
E F Salazar-Grueso1, R S Rosenberg, R P Roos
1Department of Neurology, University of Chicago, IL 60637.
Annals of Neurology
|April 1, 1988
Abstract:
A 37-year-old man with a 19-year history of progressive autosomal-dominant olivopontocerebellar degeneration developed excessive daytime sleepiness and paroxysmal episodes that clinically resembled an ictal or postictal state. Polysomnography showed sleep apnea. Long-term therapy with trazodone resulted in resolution of the paroxysmal episodes, disappearance of daytime sleepiness, and gradual improvement of sleep architecture over several months.