Advanced practice for children and young people: A systematic review with narrative summary

Robin Hyde1, Sonya MacVicar1, Tracy Humphrey1

  • 1School of Health & Social Care, Edinburgh Napier University, Edinburgh, UK.

Abstract

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Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
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