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Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
Published on: November 15, 2017
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[Progress in the application of functional materials in proteomics research].
Xiaochao Xiang1, Fenglong Jiao1, Yangjun Zhang1
1Beijing Institute of Lifeomics, Beijing Proteome Research Center, National Center for Protein Sciences(Beijing), State Key Laboratory of Proteomics, Beijing 102206, China.
Se Pu = Chinese Journal of Chromatography
|October 24, 2019
Summary
Novel functional materials are crucial for advancing proteomics methods beyond traditional limitations. These materials enhance speed, sensitivity, and accuracy, meeting new research demands in proteomic identification.
Area of Science:
- Proteomics
- Materials Science
Background:
- Traditional proteomics methods face limitations in speed, sensitivity, and accuracy.
- Increasing depth of proteomic identification presents new analytical challenges.
Purpose of the Study:
- To review recent advances in applying functional materials to proteomics.
- To highlight how functional materials overcome traditional proteomics limitations.
Main Methods:
- Review of literature on functional materials in proteomics.
- Discussion of material preparation via chemical, biochemical, electrical, magnetic, thermal, and photoirradiation methods.
Main Results:
- Functional materials offer solutions to enhance quantitative accuracy and analytical speed in proteomics.
- Novel materials are key to overcoming the limitations of traditional analytical techniques.
Conclusions:
- The development and application of functional materials are essential for the future of proteomics research.
- Functional materials enable significant progress in proteomic identification and analysis.
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