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StrateGene: object-oriented programming in molecular biology.

R E Carhart1, H D Cash, J F Moore

  • 1IntelliGenetics, Inc., Mountain View, CA 94040.

Computer Applications in the Biosciences : CABIOS
|March 1, 1988
PubMed
Summary
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Object-oriented programming (OOP) in StrateGene manages biological data for genetic engineering. This approach simplifies biological information representation and manipulation in cloning experiments.

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Molecular Biology

Background:

  • Biological information management is complex.
  • Traditional methods may lack flexibility.
  • Object-oriented programming offers potential solutions.

Purpose of the Study:

  • To describe the application of object-oriented programming (OOP) for biological data management.
  • To demonstrate OOP's utility in a genetic engineering workstation (StrateGene).

Main Methods:

  • Representing biological entities (molecules, enzymes, fragments, methods) as objects and classes.
  • Utilizing a hierarchical structure for objects and their attributes.
  • Implementing user modification and easy system updates.

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Main Results:

  • StrateGene effectively manages cloning experiment information.
  • Biological objects and their attributes are hierarchically organized and modifiable.
  • Operations are associated with objects, allowing for customization.

Conclusions:

  • OOP methodologies provide a flexible and extensible framework for biological data.
  • StrateGene demonstrates the practical application of OOP in genetic engineering.
  • This approach facilitates easier data manipulation and system evolution.