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The 20 alpha-hydroxysteroid dehydrogenase of Streptomyces hydrogenans
R L Rimsay1, G W Murphy, C J Martin
1Faculty of Medicine, Health Sciences Centre, Memorial University of Newfoundland, St. John's, Canada.
European Journal of Biochemistry
|June 1, 1988
Abstract:
In addition to the well-known 3 alpha,20 beta-hydroxysteroid dehydrogenase ('cortisone reductase'), Streptomyces hydrogenans produces a relatively stable, NAD-dependent 20 alpha-hydroxysteroid dehydrogenase of molecular mass approximately 48 kDa. This enzyme catalyzes the transfer of hydrogen from the 4-pro-S position of NADH.