[Salivary cortisol level and peri-abortion depression]
Xiaohong Zhang1, Jiangming Sheng2, Chi Huang3
1Department of Emergency, Third Xiangya Hospital, Central South University, Changsha 410013, China.
Objective:
To study the salivary cortisol level, and to analyze the correlation between salivary cortisol and peri-abortion depression in the women suffering termination of pregnancy for fetal anomaly. Methods: Comparing the difference in salivary cortisol level between the women with and without depression when they underwent termination of pregnancy for fetal anomaly in a prospective cohort study. Analyzing the correlation between salivary cortisol and peri-abortion depression through logistics regression analysis. Results: The salivary cortisol awakening response was lower in women with depression than women without depression. Based on the logistics regression analysis, the salivary cortisol awakening response showed a negative correlation with pre-abortion (OR=0.063, 95% CI 0.005 to 0.754) and post-abortion (OR=0.002, 95% CI 0.000 to 0.061) depression. Conclusion: Cortisol awakening response possesses a negative correlation with peri-abortion depression, and it is a predictive factor for post-abortion depression.
Related Concept Videos
Hypothalamic-Pituitary Axis
Disorders of the Female Reproductive System
Ovarian Cycle
Introduction to Stress and Lifestyle


