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Proteasome activator PA200 regulates myofibroblast differentiation

Vanessa Welk1, Thomas Meul1, Christina Lukas1

  • 1Comprehensive Pneumology Center (CPC), University Hospital of the Ludwig-Maximilians-University (LMU) and Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Max-Lebsche Platz 31, 81377, Munich, Germany.

Scientific Reports
|October 25, 2019
PubMed
Summary

The proteasome activator PA200 regulates myofibroblast differentiation. Its dysfunction in idiopathic pulmonary fibrosis highlights a new therapeutic target for fibrotic diseases.

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