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Updated: Jan 5, 2026

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
Published on: April 11, 2018
Non-gastrointestinal stromal tumours soft tissue sarcomas: an update
Gustavo Duarte Ramos Matos1,2, Veridiana Pires de Camargo1,3, Rodrigo Ramella Munhoz1,4
1Instituto do Câncer do Estado de São Paulo, São Paulo 01246-000, Brazil.
Abstract:
Soft tissue sarcomas (STS) encompass a diverse family of neoplasms of mesenchymal origin, marked by significant heterogeneity in terms of physiopathology, molecular characterisation, natural history and response to different therapies. This review aims to summarise the current strategies for the management of patients with STS, including surgery, systemic treatments and radiation therapy, along with considerations applicable to the most frequent subtypes, as well as particularities associated with less common and specific histologies. It also provides insights into upcoming strategies to tackle this challenging group of diseases.
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