Related Experiment Video

Updated: Jan 5, 2026

Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression
04:36

Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression

Published on: January 12, 2024

1.5K

Hypertension in diabetes and the risk of cardiovascular disease

Nirmal Sunkara1, Chowdhury H Ahsan2

  • 1Fellow in Vascular Medicine and Advanced Endovascular and Structural Heart Interventions, Wellmont CVA Heart Institute Kingsport, Kingsport, Tennessee.

Cardiovascular Endocrinology
|October 25, 2019
PubMed

Insights

Hypertension (HTN) is a key risk factor for cardiovascular disease, sharing pathways with diabetes within metabolic syndrome. Managing HTN is crucial for preventing cardiovascular events, especially when diabetes is present.

Area of Science:

  • Cardiology
  • Endocrinology
  • Metabolic Syndrome Research

Background:

  • Hypertension (HTN) is a significant risk factor for cardiovascular disease (CVD).
  • HTN shares common pathogenic pathways with diabetes, contributing to the metabolic syndrome.
  • Combined HTN and diabetes increase CVD risk beyond individual factors.

Purpose of the Study:

  • To highlight the importance of hypertension management within the context of metabolic syndrome.
  • To discuss the role of hypertension in cardiovascular risk prediction.
  • To acknowledge the ongoing debate regarding hypertension treatment targets following JNC-8 guidelines.

Main Methods:

  • Review of existing literature on hypertension, diabetes, and cardiovascular disease.
  • Analysis of the interplay between metabolic syndrome components.
  • Examination of current hypertension treatment guidelines and controversies.

Main Results:

  • Hypertension is a readily diagnosable component of metabolic syndrome, offering a target for intervention.
  • The combination of hypertension and diabetes significantly elevates cardiovascular disease risk.
  • Recent guidelines (JNC-8) have initiated discussions on optimal blood pressure management goals.

Conclusions:

  • Effective management of hypertension is critical for cardiovascular disease prevention.
  • Addressing hypertension is a key strategy within metabolic syndrome management.
  • Further research and consensus are needed on hypertension treatment targets.

Keywords:
diabeteshypertensionrisk of cardiovascular disease

More Related Videos

Modeling and Evaluation of Murine Diabetic Cardiomyopathy Model06:22

Modeling and Evaluation of Murine Diabetic Cardiomyopathy Model

Published on: November 29, 2024

1.3K
Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes07:22

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes

Published on: March 7, 2025

669

Related Concept Videos

Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
3.6K
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
837
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
427
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
694
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.0K
Hypertension I: Introduction01:28

Hypertension I: Introduction

Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
646