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Effect of motor vehicle pollution on lung function, fractional exhaled nitric oxide and cognitive function among
S A Meo1, M Aldeghaither, K A Alnaeem
1Department of Physiology, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia. sultanmeo@hotmail.com.
Objective:
Motor vehicle emission is a major cause of environmental pollution, which threatens human health. This study aimed to investigate the effect of motor vehicle pollution on lung function, fractional exhaled nitric oxide (FeNO), and cognitive function among students studying in a school located in a traffic-polluted area.
Subjects And Methods:
In this cross-sectional study, students were recruited based on their apparent healthy status, same age, gender, height, weight, ethnicity, and homogenous educational, socio-economic status, and living backgrounds. Initially, 200 students, 100 from school-1 located in motor vehicle polluted area (exposed group) and 100 from school-2, located away from motor vehicle polluted area (control group) were recruited. After clinical history, 68 students were selected, 34 from school-1 and 34 from school-2. These students were exposed to motor vehicle pollution for 6 h a day, 5 days a week for a total period of 2 years. Lung function test parameters were recorded using a Spirometer, fractional exhaled nitric oxide (FeNO) was measured by Niox Mino, and cognitive function was recorded using the Cambridge Neuropsychological Test Automated Battery (CANTAB).
Results:
The lung function test parameters, Forced Vital Capacity (FVC) (p=0.03); Forced Expiratory Volume in First Second (FEV1) (p=0.02); and cognitive function parameter motor screening task (MOT) mean latency (p=0.04) were decreased among the students who were studying in school situated in traffic-polluted area compared to those students who were studying in school which was located away from the traffic-polluted area. However, no significant difference was noted in FeNO between the groups.
Conclusions:
Motor vehicle pollution showed an association with decreased respiratory and cognitive functions among students studying in schools located in traffic-polluted areas. Environmental protection organizations must establish standards to minimize motor vehicle pollutants and develop strategies to control vehicle emission to reduce pollution and disease burden.
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