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Postoperative antibiotic prescriptions reduced infection risk following facial plastic surgery. However, antibiotic use patterns require further examination, especially for high-risk patient groups to refine best practices.

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Area of Science:

  • Plastic Surgery
  • Infectious Disease Epidemiology
  • Pharmacology

Background:

  • Antibiotic use after facial plastic surgery lacks standardized evidence-based guidelines.
  • There is a need for large-scale data to inform best practices for postoperative antibiotic prescriptions.

Purpose of the Study:

  • To evaluate antibiotic prescribing patterns post-facial plastic surgery.
  • To determine the association between antibiotic use and infection rates after nasal and oculoplastic procedures.

Main Methods:

  • Retrospective cohort study of 294,039 patients undergoing facial plastic surgery (2007-2015).
  • Analysis of IBM MarketScan databases to assess antibiotic prescriptions and infectious complications.
  • Multivariable logistic regression used to identify factors associated with antibiotic use and infection risk.

Main Results:

  • 45.2% of patients received postoperative antibiotics; 55.3% for nasal, 14.7% for oculoplastic procedures.
  • Postoperative antibiotics were linked to a significantly decreased risk of infection (nasal: aOR 0.144; oculoplastic: aOR 0.254).
  • Increased antibiotic duration did not correlate with reduced infection rates; high-risk patients were less likely to receive antibiotics.

Conclusions:

  • Postoperative antibiotic use is associated with lower infection rates in facial plastic surgery.
  • Population-level data is crucial for developing evidence-based antibiotic guidelines.
  • Further research is needed on antibiotic use patterns for high-risk populations to prevent wound infections.