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bWGR: Bayesian Whole-Genome Regression
Alencar Xavier1,2, William M Muir2, Katy M Rainey2
1Corteva Agrisciences, 8305 NW 62nd Ave, Johnston IA.
Motivation:
Whole-genome regressions methods represent a key framework for genome-wide prediction, cross-validation studies, and association analysis. The bWGR offers a compendium of Bayesian methods with various priors available, allowing users to predict complex traits with different genetic architectures.
Results:
Here we introduce bWGR, an R package that enables users to efficient fit and cross-validate Bayesian and likelihood whole-genome regression methods. It implements a series of methods referred to as the Bayesian alphabet under the traditional Gibbs sampling and optimized Expectation-Maximization. The package also enables fitting efficient multivariate models and complex hierarchical models. The package is user-friendly and computational efficient.
Availability And Implementation:
bWGR is an R package available in the CRAN repository. It can be installed in R by typing: install.packages("bWGR").
Supplementary Information:
Supplementary data are available at Bioinformatics online.
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