Related Experiment Video
Updated: Jan 5, 2026

Frailty Assessment in an Aging Mouse Model
Published on: September 23, 2025
A Socratic Inquiry Into the Nature of Frailty
1Division of Biostatistics and Bioinformatics, Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland.
Abstract:
In Plato's dialogues, Socrates, the protagonist, attempts to bring out the essential nature of an idea or a concept by engaging in a dialogue with the other characters. He asks probing questions of them to challenge their unquestioned assumptions and to eliminate flaws in their thinking. A hallmark of the dialogues is that Socrates himself never provides a final answer regarding the nature of the idea under discussion. Inspired by the power of the Socratic model to illumine one's thinking on difficult concepts, we have developed a short dialogue examining the nature of geriatric frailty. Our goal is to communicate, in a lively and nontechnical style, some of the fundamental challenges in studying frailty in older adults. Those acquainted with Plato's dialogues will recognize the resemblance to the initial segment of The Republic,1 which takes place in the house of a wealthy merchant named Cephalus. J Am Geriatr Soc 67:2455-2457, 2019.
More Related Videos
05:53Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
04:00Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles
Published on: July 26, 2024
Related Concept Videos
Aging
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Erikson's Theory on Socioemotional Development during Adulthood
Intimacy Versus Isolation in Early Adulthood
Individuals in early...
The Effect of Aging on Tissues
Introspection
Cognitive Development During Adulthood
Concepts of Health and Illness