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A cost-effectiveness analysis of the Prediabetes Intervention Package (PIP) in primary care: a New Zealand pilot
Deborah Connor1, Kirsten Coppell2, Andrew Gray3
1Immediate Past President, Diabetes New Zealand, Wellington.
Insights
The Prediabetes Intervention Package (PIP) is a cost-effective lifestyle program for weight loss in prediabetes patients. This nurse-led intervention helps prevent progression to type 2 diabetes.
Area of Science:
- Public Health
- Health Economics
- Preventive Medicine
Background:
- Prediabetes poses a significant risk for developing type 2 diabetes.
- Lifestyle interventions are crucial for managing prediabetes and preventing disease progression.
- Primary care settings offer opportunities for scalable health interventions.
Purpose of the Study:
- To evaluate the cost-effectiveness of the Prediabetes Intervention Package (PIP).
- To assess the PIP's effectiveness in promoting weight loss among individuals with prediabetes.
- To determine the intervention's potential to prevent or delay the onset of type 2 diabetes.
Main Methods:
- A cost-effectiveness analysis was performed from a health funder perspective.
- Data were collected over six months, with missing data imputed using multiple imputation.
- Intention-to-treat principles were applied to calculate weight change; three cost scenarios were modeled.
Main Results:
- The PIP intervention resulted in a statistically significant median weight loss of 1.87kg at six months.
- The incremental cost-effectiveness ratio (ICER) was NZ$170.90 per kilogram of weight loss.
- Lower-cost scenarios showed ICERs ranging from NZ$95.33 to NZ$120.74 per kilogram of weight loss.
Conclusions:
- The primary care nurse-delivered PIP is a cost-effective strategy for weight loss in prediabetes.
- The intervention shows promise in preventing or delaying the progression to type 2 diabetes.
- PIP represents a valuable public health tool for managing prediabetes in primary care settings.
Aims:
To estimate the cost-effectiveness of the Prediabetes Intervention Package (PIP), a multilevel primary care nurse-delivered prediabetes lifestyle intervention programme was piloted in Hawke's Bay, New Zealand. The goal of the intervention was weight loss and prevention of progression from prediabetes to type 2 diabetes.
Methods:
A cost-effectiveness evaluation was conducted from a health funder perspective using 2015 NZ$ with costs and per kilogram (kg) weight change at six months analysed at an individual participant level. Missing six-month data were imputed using multiple imputation adjusted for baseline characteristics. Change in weight was calculated following intention-to-treat principles. Three lower-cost scenarios were modelled.
Results:
Using multiple imputation and bootstrapping, there was a statistically significant median difference in weight between the intervention and control groups of 1.87kg (95% CI 0.54, 3.15) at six months. The incremental cost-effectiveness ratio (ICER) was NZ$170.90 (95% CI 100.37, 553.93) per 1kg of weight loss. ICERs for the lower-cost scenarios ranged from NZ$95.33 (95% CI 56.12, 308.36) to $NZ120.74 (95% CI 71.04, 391.60).
Conclusion:
The primary care nurse-delivered PIP intervention is likely to be a cost-effective weight loss strategy for preventing or delaying progression to type 2 diabetes in people with prediabetes.
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