Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stem Cell Culture01:17

Stem Cell Culture

6.0K
Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
6.0K
Embryonic Stem Cells00:57

Embryonic Stem Cells

4.6K
Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
4.6K
Mesenchymal Stem Cells01:19

Mesenchymal Stem Cells

5.4K
Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their...
5.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evolving Landscapes, Shifting Narratives: Understanding Taiwanese News Media Portrayals of LGBTQ+ Populations from 2010 to 2021.

Journal of homosexuality·2026
Same author

A simulation-based study of 3D printing angle optimization by integrating deep learning and NSGA-III for prosthesis and retainer manufacturing.

The Journal of prosthetic dentistry·2026
Same author

A Multifunctional Therapeutic Platform: Ce/Zn/Sr-Doped Mesoporous Bioactive Glass Nanoparticles for Bone Repair.

International journal of molecular sciences·2026
Same author

From Discrimination to Unmet Healthcare Needs and Care (Dis)Satisfaction among Urban-Dwelling Indigenous Taiwanese Adults: A Path Analysis.

Journal of racial and ethnic health disparities·2026
Same author

School Closure, Different Aspects of Relational Life, and Adolescent Psychosomatic Complaints: Evidence From Programme for International Student Assessment 2022.

The Journal of adolescent health : official publication of the Society for Adolescent Medicine·2025
Same author

Cumulative (dis)advantages in cognitive health: rural/urban residency, household registration status, and cognitive aging among older Chinese adults.

The journals of gerontology. Series B, Psychological sciences and social sciences·2025

Related Experiment Video

Updated: Jan 5, 2026

Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth
02:33

Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth

Published on: May 17, 2024

2.5K

Stem Cells from Human Exfoliated Deciduous Teeth: A Concise Review.

Chih-Sheng Ko1, Jen-Hao Chen2,3, Wen-Ta Su4

  • 1PhytoHealth Corporation, Taipei, Taiwan.

Current Stem Cell Research & Therapy
|October 26, 2019
PubMed
Summary

Stem Cells from Human Exfoliated Deciduous Teeth (SHED) are versatile ectodermal stem cells with embryonic stem cell markers. Their high proliferation and multi-differentiation capacity make them promising for regenerative medicine and tissue engineering.

Keywords:
ESCsHSCsStem cells from human exfoliated deciduous teethbankingdental stem cellsisolation.

More Related Videos

Author Spotlight: Importance of Single Cell Sorting in Isolating Purified Populations of Mesenchymal Stem Cells
13:44

Author Spotlight: Importance of Single Cell Sorting in Isolating Purified Populations of Mesenchymal Stem Cells

Published on: November 10, 2023

2.5K
Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy
11:02

Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy

Published on: April 13, 2022

4.0K

Related Experiment Videos

Last Updated: Jan 5, 2026

Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth
02:33

Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth

Published on: May 17, 2024

2.5K
Author Spotlight: Importance of Single Cell Sorting in Isolating Purified Populations of Mesenchymal Stem Cells
13:44

Author Spotlight: Importance of Single Cell Sorting in Isolating Purified Populations of Mesenchymal Stem Cells

Published on: November 10, 2023

2.5K
Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy
11:02

Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy

Published on: April 13, 2022

4.0K

Area of Science:

  • Biomedical Engineering
  • Stem Cell Biology
  • Regenerative Medicine

Background:

  • Stem Cells from Human Exfoliated Deciduous Teeth (SHED) are mesenchymal stem cells derived from the neural crest.
  • SHED share cell markers (OCT4, NANOG) with Embryonic Stem Cells (ESCs).

Purpose of the Study:

  • To review the isolation and banking of SHED.
  • To discuss the application of SHED in regenerative medicine and tissue engineering.

Main Methods:

  • Isolation and characterization of SHED.
  • In vitro and in vivo studies on SHED potential.

Main Results:

  • SHED exhibit high proliferation rates, telomerase activity, and multi-differentiation capacity.
  • SHED form sphere-like clusters, indicating stemness.
  • SHED show significant potential in regenerative medicine and tissue engineering.

Conclusions:

  • SHED are a highly plastic and promising stem cell source for biomedical applications.
  • Further research into SHED banking and clinical applications is warranted.