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Related Concept Videos

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Updated: Jan 5, 2026

Nerve Stimulator-guided Injection of Autologous Stem Cells Near the Equine Left Recurrent Laryngeal Nerve
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Recurrent Laryngeal Nerve Stimulator.

Andreas H Mueller1, Claus Pototschnig2

  • 1Otorhinolaryngology, SRH Wald-Klinikum, Strasse des Friedens 122, Gera 07548, Germany.

Otolaryngologic Clinics of North America
|October 26, 2019
PubMed
Summary
This summary is machine-generated.

Electrical stimulation of the recurrent laryngeal nerve offers a promising therapy for glottal enlargement. Detecting viable reinnervation is crucial for selecting patients who will benefit from laryngeal pacemaker implantation.

Keywords:
Implantable neurostimulatorLaryngeal pacingLarynxNeurostimulationVocal fold paralysis/paresis therapy

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Area of Science:

  • Neurology
  • Otolaryngology
  • Biomedical Engineering

Background:

  • Conventional surgical glottal enlargement has limitations.
  • Electrical stimulation of the recurrent laryngeal nerve (RLN) presents a viable alternative.
  • Aberrant reinnervation, often unfavorable for vocal fold movement recovery, is essential for laryngeal pacemaker function.

Purpose of the Study:

  • To highlight the importance of aberrant reinnervation for laryngeal pacemaker efficacy.
  • To emphasize the need for diagnostic tools to detect viable RLN reinnervation.
  • To guide patient selection for laryngeal pacemaker implantation.

Main Methods:

  • Review of existing literature on RLN stimulation and reinnervation.
  • Analysis of the role of aberrant reinnervation in clinical outcomes.
  • Discussion of diagnostic approaches for assessing nerve viability.

Main Results:

  • Aberrant reinnervation is critical for successful laryngeal pacemaker performance.
  • Current diagnostic methods may not adequately detect the necessary reinnervation.
  • Viable reinnervation on at least one vocal fold is a key indicator for successful treatment.

Conclusions:

  • Effective patient selection for laryngeal pacemakers relies on identifying viable reinnervation.
  • Development of new diagnostic tests is necessary for reliable detection of reinnervation.
  • RLN electrical stimulation holds significant therapeutic potential when guided by appropriate diagnostics.