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Desquamative gingivitis responding to treatment with tetracycline: a pilot study
1Department of Oral Surgery and Oral Medicine, Dental Faculty, University of Oslo, Norway.
Scandinavian Journal of Dental Research
|June 1, 1988
Summary
Doxycycline monohydrate significantly improved desquamative gingivitis symptoms in three patients. This suggests plaque may play a role in this condition, warranting further investigation into its etiology.
Area of Science:
- Oral Medicine
- Periodontology
- Dermatology
Background:
- Desquamative gingivitis presents with significant clinical signs and symptoms.
- The exact etiology of desquamative gingivitis remains incompletely understood.
- Plaque substances are being investigated for their potential role.
Purpose of the Study:
- To evaluate the efficacy of doxycycline monohydrate in treating desquamative gingivitis.
- To explore the potential role of plaque in the pathogenesis of desquamative gingivitis.
Main Methods:
- Three patients diagnosed with desquamative gingivitis were treated.
- Treatment involved daily administration of 100 mg doxycycline monohydrate.
- Treatment duration was 8 weeks.
Main Results:
- Remarkable regression of clinical signs and symptoms was observed in all three patients.
- Patients showed significant improvement following doxycycline monohydrate treatment.
Conclusions:
- Doxycycline monohydrate appears to be an effective treatment for desquamative gingivitis.
- Plaque substances are postulated as potential etiologic factors in desquamative gingivitis.