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CD4CD8αα IELs: They Have Something to Say

Chao Zhou1, Yuan Qiu1, Hua Yang1

  • 1Department of General Surgery, Xinqiao Hospital, Army Medical University, Chongqing, China.

Frontiers in Immunology
|October 26, 2019
PubMed
Summary

Intraepithelial lymphocytes (IELs), specifically CD4CD8αα IELs, are crucial for gut immune balance, exhibiting both immunosuppression and cytotoxicity. Their role in inflammatory bowel disease (IBD) warrants further investigation.

Keywords:
CD4CD8αα intestinal intraepithelial lymphocytes (CD4CD8αα IELs)inflammatory bowel disease (IBD)intestinal microbestranscription factorsvitamin D receptor (VDR)

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