Related Experiment Videos
The prevalence of cleft lip and plate in Japanese
1Second Department of Oral and Maxillofacial Surgery, School of Dentistry, Aichi-Gakuin University, Nagoya, Japan.
Insights
The prevalence of cleft lip and palate (CL/P) in Japanese newborns is 1.46 per 1000 births. This study investigated over 43,000 infants to determine these birth defect rates.
Area of Science:
- Medical Science
- Pediatrics
- Genetics
Background:
- Cleft lip and palate (CL/P) are common congenital anomalies.
- Understanding the prevalence of CL/P is crucial for public health planning and resource allocation.
- Previous data on CL/P prevalence in the Japanese population requires updated investigation.
Purpose of the Study:
- To determine the birth prevalence of cleft lip and palate (CL/P) in Japanese infants.
- To classify the types of CL/P observed in the study population.
Main Methods:
- A retrospective study analyzing birth records of 43,821 infants born in Japan between January 1, 1985, and December 31, 1985.
- Classification of cleft types was performed on a subset of 326 infants born between January 1, 1981, and December 31, 1985.
Main Results:
- A total birth prevalence of 1.46 per 1000 infants (0.146%) was found for CL/P.
- Among 326 classified cases, cleft lip and palate (CLP) was the most common type (47.3%), followed by cleft lip (CL) (34.0%) and cleft palate (CP) (18.7%).
Conclusions:
- The study provides current prevalence data for CL/P among Japanese newborns.
- CLP is the predominant form of clefting in this population.
- These findings are essential for epidemiological studies and clinical management of CL/P in Japan.
Abstract:
To determine the prevalence of cleft lip and palate (CL/P) among the Japanese, 43,821 babies born between 1 January, 1985, and 31 December, 1985, were investigated. Sixty-four infants (0.146%) were found to demonstrate these abnormalities, a birth prevalence rate of 1.46/1000. Among 326 infants in whom it was possible to classify the types of cleft, born between 1 January, 1981, and 31 December, 1985, there were 111 (34.0%) with cleft lip (CL), 154 (47.3%) with cleft lip and palate (CLP) and 61 (18.7%) with cleft palate (CP).