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Autoimmune pancreatitis: an update
Ashish Khandelwal1, Dai Inoue2, Naoki Takahashi3
1Department of Radiology, Mayo Clinic, 200 First St, Rochester, MN, 55902, USA.
Objective:
Since the time of inception of autoimmune pancreatitis (AIP), our knowledge of autoimmune pancreatitis has expanded significantly. The aim of this review is to provide an update on clinical manifestations, diagnosis, imaging features, and treatment of AIP.
Background And Clinical Significance:
Type 1 AIP is the pancreatic manifestation of IgG4-related systemic disease, which can be diagnosed using a combination of clinical, histopathological, pancreatic imaging findings in conjunction with manifestation in other organs, as well of responsiveness to steroid treatment. It is vital to differentiate AIP from pancreatic cancer since both can mimic each other clinically and radiologically. Type 2 AIP is a rare but distinct subtype of AIP which occurs mostly in the younger patient.
Conclusion:
AIP is steroid-responsive chronic pancreatitis with distinct manifestations on imaging.
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