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Related Experiment Video

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Fabrication of Refractive-index-matched Devices for Biomedical Microfluidics
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Microfluidic Platforms toward Rational Material Fabrication for Biomedical Applications.

Qilong Zhao1, Huanqing Cui1, Yunlong Wang1

  • 1Institute of Biomedical & Health Engineering, Shenzhen Institutes of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS), Shenzhen, 518035, China.

Small (Weinheim an Der Bergstrasse, Germany)
|October 26, 2019
PubMed
Summary

Microfluidics enables precise fabrication of micro/nanomaterials for biomedicine. These advanced materials offer enhanced performance in diagnostics, drug delivery, and tissue engineering applications.

Keywords:
biomedicinefibersfilmsmicrofluidicsparticles

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Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Nanotechnology

Background:

  • Micro/nanomaterials are crucial for advancements in pharmaceutics, diagnostics, and therapeutics.
  • Tailoring material properties requires precise control over geometry, structure, and composition.
  • Existing manufacturing techniques face challenges in meeting these demands for specialized biomedical applications.

Purpose of the Study:

  • To review the progress of microfluidics in fabricating diverse micro/nanomaterials.
  • To highlight the applications of microfluidic-derived materials in various biomedical fields.
  • To discuss future directions for microfluidic platforms in advanced material generation.

Main Methods:

  • Microfluidics platforms for high-throughput fabrication of micro/nanomaterials.
  • Control over material dimensions (0D, 1D, 2D/3D) and properties.
  • Integration of diverse materials and techniques with microfluidic systems.

Main Results:

  • Microfluidics enables precise control over geometry, structure, and composition of micro/nanomaterials.
  • Fabricated materials include particles, fibers, films, and bulk materials.
  • Demonstrated applications in diagnostics, drug delivery, organs-on-chips, and tissue engineering.

Conclusions:

  • Microfluidics is a powerful technology for designing and manufacturing advanced micro/nanomaterials for biomedical use.
  • Continued integration of new materials and techniques will enhance material performance and functionalities.
  • Future microfluidic platforms promise superior properties and on-demand functionalities for next-generation biodevices.