Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

CA-125 serum concentrations during the menstrual cycle.

W Jäger1, C Meier, L Wildt

  • 1University of Erlangen, Federal Republic of Germany.

Fertility and Sterility
|August 1, 1988
PubMed
Summary

CA-125 serum levels increase with dominant follicle growth during the menstrual cycle in healthy women. This pattern was absent during hormonal contraceptive treatment, suggesting CA-125 is linked to ovarian cyclic changes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Chemical treatment rescues reduced growth of the autoimmune mutant chs3-2D without compromising its immune responses.

Plant biology (Stuttgart, Germany)·2026
Same author

Bone microstructure and TBS in diabetes: what have we learned? A narrative review.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2025
Same author

Minimally invasive lateral plating for diaphyseal fractures with extension into the proximal humerus and its implications for the deltoid muscle and its distal insertion: functional analysis and MR-imaging.

BMC musculoskeletal disorders·2023
Same author

In infertile women with subclinical hypothyroidism, with or without thyroid peroxidase antibodies, serum TSH during pregnancy follows preconception values and thyroid hormones remain stable.

Human reproduction open·2023
Same author

Measurement of polarization observables <math></math>, <math></math>, and <math></math> in <math></math> and <math></math> photoproduction off quasi-free nucleons.

The European physical journal. A, Hadrons and nuclei·2023
Same author

Single <math></math> production off neutrons bound in deuteron with linearly polarized photons.

The European physical journal. A, Hadrons and nuclei·2021

Area of Science:

  • Gynecology
  • Reproductive Endocrinology
  • Oncology Biomarkers

Background:

  • CA-125 is an ovarian cancer biomarker found in healthy women and benign gynecologic conditions.
  • Prior research suggests CA-125 production correlates with ovarian proliferative activity.

Purpose of the Study:

  • To investigate the pattern of CA-125 secretion in healthy women throughout the menstrual cycle.
  • To assess CA-125 levels during hormonal contraceptive treatment.

Main Methods:

  • Serum CA-125 concentrations were monitored in 13 healthy women.
  • Measurements were taken during their natural menstrual cycle and during hormonal contraceptive use.

Main Results:

  • CA-125 serum concentrations showed a distinct increase parallel to dominant follicle growth during the menstrual cycle.

Related Experiment Videos

  • This cyclical increase in CA-125 was not observed when women were on hormonal contraceptives.

    • Conclusions:

    • CA-125 serum levels appear to be influenced by cyclic physiological changes within the female reproductive system.
    • The findings suggest CA-125's utility as a marker for ovarian activity, distinct from its role in cancer detection.