Cobalt-Catalyzed Oxidative Annulation of Benzothiophene-[b]-1,1-dioxide through Diastereoselective Double C-H
Subban Kathiravan1, Ian A Nicholls1
1Bioorganic & Biophysical Chemistry Laboratory, Department of Chemistry & Biomedical Sciences and Linnaeus University Centre for Biomaterials Chemistry , Linnaeus University , SE-391 82 Kalmar , Sweden.
Abstract:
The use of inexpensive base metal catalysis to perform C-H activation is an active field of research in organic synthesis. Described herein is a sustainable cobalt-catalyzed diastereoselective oxidative annulation/double C-H activation of benzothiophene-[b]-1,1-dioxide with aminoquinolinamides under mild reaction conditions for the synthesis of annulated benzothiophenes.
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