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Repeat Episodes of Symptomatic Urethritis Due to a Uropathogenic Meningococcal Clade
Jose A Bazan, Yih-Ling Tzeng1, David S Stephens
1Division of Infectious Diseases, Departments of Medicine.
Abstract:
In 2015, we identified a non-groupable clade of Neisseria meningitidis that causes urethritis in men (the US_NmUC). Because repeat infection is common with Neisseria gonorrhoeae, we examined whether reinfection also occurs with the US_NmUC. We provide evidence that men are susceptible to repeat episodes of urethritis from the US_NmUC.
Insights
Men can experience repeat urethritis infections from Neisseria meningitidis (US_NmUC). This finding is important as it suggests similar reinfection patterns to Neisseria gonorrhoeae.
Area of Science:
- Microbiology
- Infectious Diseases
- Urology
Background:
- Neisseria meningitidis is a bacterium that can cause various infections.
- A specific clade, the US_NmUC, has been identified as a cause of urethritis in men.
- Neisseria gonorrhoeae, another bacterium, is known for causing recurrent urethritis.
Purpose of the Study:
- To investigate the potential for repeat infections with the US_NmUC in men.
- To compare the infection patterns of US_NmUC with those of Neisseria gonorrhoeae.
Main Methods:
- The study examined clinical data and patient histories.
- Epidemiological analysis was used to identify repeat infection cases.
Main Results:
- Evidence suggests that men are susceptible to multiple episodes of urethritis caused by the US_NmUC.
- This indicates a pattern of reinfection similar to Neisseria gonorrhoeae.
Conclusions:
- The US_NmUC can cause recurrent urethritis in men.
- Understanding reinfection is crucial for managing Neisseria meningitidis urethritis.
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