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Updated: Jan 5, 2026

Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury
Published on: February 15, 2022
Prognostic indicators in cats with septic peritonitis (2002-2015): 83 cases
Katherine Maria Scotti1, Amy Koenigshof1, Loren S H Sri-Jayantha2
1Michigan State University Veterinary Medical Center, East Lansing, Missouri.
Objective:
To identify physical exam findings, clinicopathological parameters, time to surgery, empirical antimicrobial use, and culture results that could be associated with outcome in cats with septic peritonitis (SP).
Design:
Retrospective cohort study of cats from 2002 to 2015.
Setting:
Four university teaching hospitals.
Animals:
Eighty-three cats diagnosed with SP by cytology or culture.
Interventions:
None MEASUREMENTS AND MAIN RESULTS: Fifty-eight cats survived to discharge (69.9%); 1 cat was euthanized in surgery; 20 were euthanized postoperatively; 4 cats suffered cardiac arrest after surgery. The most common etiology of SP was secondary SP due to gastrointestinal perforation (49.4%), followed by primary SP (22.3%). Mean blood glucose concentration was significantly different between survivors and nonsurvivors (P = 0.006). Cats that received appropriate empirical antibiotic therapy were 4.4 times more likely to survive than cats that did not receive appropriate antibiotics (P = 0.018).
Conclusions:
As previously documented, SP secondary to gastrointestinal leakage was the most common etiology. In this population, cats with a higher blood glucose concentration on presentation had a worse prognosis. Cats that received appropriate empirical antimicrobial therapy were more likely to survive.

