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Trapping endothelin-1 to hunt down cardiovascular disease?

Bernhard Wernly1, Christian Jung2

  • 1Clinic of Internal Medicine II, Department of Cardiology, Paracelsus Medical University of Salzburg, Salzburg, Austria.

Drug Discovery Today
|October 27, 2019
PubMed
Summary

No abstract available in PubMed .

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Endothelins (ETs) are potent vasoactive peptides critical in the human body's various physiological and pathological processes. One of the most promising therapeutic strategies for treating pulmonary arterial hypertension (PAH) involves counteracting the effects of these endothelins using a class of drugs known as endothelin receptor antagonists.
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