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Chronic ulcerative stomatitis: A systematic review of the clinical and microscopic features
T-M Ferrisse1, D-C Travassos, A-F Rocha
1Department of Diagnosis and Surgery Univ Estadual Paulista (UNESP) CEP 14801-903, Araraquara, Sao Paulo, Brazil andreiabufalino17@gmail.com.
Background:
the purpose of this study was to perform a systematic review regarding clinical and histopathological characteristics, immunopathological findings, and treatment for chronic ulcerative stomatitis (CUS).
Material And Methods:
articles in English, published from January 1962 up to November 2017, assessing clinical and immunological features, treatment, and follow-up of patientes with CUS, were retrieved from three databases (PubMed, Cochrane Library and SCOPUS). A manual literature search was also conducted. A total of 12 studies met inclusion criteria, therefore, were analyzed in this review.
Results:
CUS shares similiar clinical and microscopic features to those found in oral lichen planus (OLP) and oral lichenoid lesions (OLL). Hence, direct immunofluorescence (DIF) is indispensable to define a final diagnosis. Due to the poor sample availability in the current literature, it is not possible to accurately confirm the prevalence and features of CUS.
Conclusion:
in order to better evaluate this condition's findings, further studies with a greater amount of similar immune-mediated diseases should be performed.
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