Sudden cardiac arrest as the initial presentation for left ventricular noncompaction cardiomyopathy
Avaneesh Jakkoju1, Rakesh Jakkoju1, Vishnupriya Kuchana1
1Section of Cardiology, Department of Medicine, Louisiana State University Health Science CenterNew OrleansLouisiana.
Proceedings (Baylor University. Medical Center)
|October 29, 2019
Summary
Sudden cardiac arrest in an identical twin prompted diagnosis of left ventricular noncompaction cardiomyopathy. This rare condition affects heart muscle structure, leading to heart failure and requiring advanced treatment.
Area of Science:
- Cardiology
- Genetics
- Cardiovascular Medicine
Background:
- Sudden cardiac arrest (SCA) in young individuals necessitates thorough etiological investigation.
- Genetic predisposition to cardiac conditions is increasingly recognized, particularly in familial cases.
Observation:
- An identical twin experienced SCA, mirroring a previous event in his sibling.
- Diagnostic workup revealed left ventricular noncompaction (LVNC) and severely reduced ejection fraction in both twins.
- Coronary arteriogram was normal, excluding ischemic causes.
Findings:
- Both twins presented with SCA, ventricular fibrillation, and subsequent diagnosis of heart failure with reduced ejection fraction.
- Transthoracic echocardiography suggested left ventricular noncompaction, characterized by prominent trabeculae.
- Treatment included guideline-directed medical therapy and an implantable cardioverter-defibrillator.
Implications:
- This case highlights the potential genetic link in left ventricular noncompaction cardiomyopathy.
- Early diagnosis and management are crucial for patients with LVNC to prevent life-threatening arrhythmias.
- Further research is needed to clarify the nosological status of LVNC versus dilated cardiomyopathy.
Keywords:
Genetic cardiomyopathyheart failure with reduced ejection fractionleft ventricular noncompaction cardiomyopathysudden cardiac arrestMore Related Videos
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