Measurement of mRNA therapeutics: method development and validation challenges

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Probe-based Real-time PCR Approaches for Quantitative Measurement of microRNAs
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Neil Henderson1, Amanda Wilson2

  • 1Translational Biomarkers & Bioanalysis, Clinical Pharmacology Biologics & Bioanalytics, Clinical Pharmacology & Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.

Bioanalysis
|October 29, 2019
PubMed

Keywords:
branched DNA (bDNA)modified messenger RNA (mRNA)quantitative reverse transcription PCR (qRT-PCR)regulatory bioanalysis

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