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[The confidence affects willingness to use pre-exposure prophylaxis among MSM, based on Path analysis]

T Luo1, Hailili Gulisiya, Z Chen

  • 1Department of Epidemiology and Health Statistics, College of Public Health, Xinjiang Medical University, Urumqi 830011, China.

Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi
|October 29, 2019
PubMed

Insights

Confidence in pre-exposure prophylaxis (PrEP) directly influences willingness to use PrEP among men who have sex with men (MSM). Targeted interventions can boost confidence and PrEP use, reducing HIV risk.

Area of Science:

  • Public Health
  • Epidemiology
  • Behavioral Science

Background:

  • Pre-exposure prophylaxis (PrEP) is a key HIV prevention strategy.
  • Understanding factors influencing PrEP uptake among men who have sex with men (MSM) is crucial.
  • Confidence in PrEP efficacy and accessibility impacts its adoption.

Purpose of the Study:

  • To analyze how confidence in PrEP influences willingness to use PrEP among MSM.
  • To investigate direct and indirect pathways affecting PrEP willingness using structural equation modeling (SEM).

Main Methods:

  • A questionnaire survey was administered to 513 MSM in Urumqi.
  • Snowball sampling was used for participant recruitment.
  • Structural equation modeling (SEM) with path analysis was employed to analyze relationships.

Main Results:

  • The SEM model demonstrated good fit.
  • Confidence in PrEP directly influenced willingness to use PrEP.
  • Partner attitudes, emotions, sexual behavior, AIDS severity, and HIV prevention behavior also played significant roles, some indirectly through confidence.
  • Population HIV infection rates indirectly affected willingness via confidence.

Conclusions:

  • Confidence is a key determinant of PrEP willingness in MSM.
  • Targeted interventions should focus on enhancing confidence to improve PrEP uptake.
  • SEM effectively revealed mediating effects, offering deeper insights than traditional regression.
Keywords:
ConfidenceMen who have sex with menPath analysisPre-exposure prophylaxisWillingness

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