Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Neuroplasticity01:01

Neuroplasticity

1.4K
Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
1.4K
Plasticity00:58

Plasticity

2.8K
Plasticity is the property where an object loses its elasticity and undergoes irreversible deformation, even after the deformation forces are eliminated. If a material deforms irreversibly without increasing stress or load, then this is called ideal plasticity. For example, when a force is applied to an aluminum rod, it changes its shape, but it does not return to its original shape once the force is removed. Plastic deformation or ductility is thus a permanent deformation or change in the...
2.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Mind-Matter Dichotomy: A Persistent Challenge for Neuroscientific and Philosophical Theories.

The European journal of neuroscience·2025
Same author

The functional role of oscillatory dynamics in neocortical circuits: A computational perspective.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Age dependent deficits in speech recognition in quiet and noise are reflected in MGB activity and cochlear onset coding.

NeuroImage·2024
Same author

Association of Neurogranin and BACE1 With Clinical Cognitive Decline in Individuals With Subjective Cognitive Decline.

Neurology·2024
Same author

Symptomatic Clusters Related to Amyloid Positivity in Cognitively Unimpaired Individuals.

Journal of Alzheimer's disease : JAD·2024
Same author

Neural Adaptation at Stimulus Onset and Speed of Neural Processing as Critical Contributors to Speech Comprehension Independent of Hearing Threshold or Age.

Journal of clinical medicine·2024

Related Experiment Video

Updated: Jan 5, 2026

Inducing Long-Term Plasticity of Intrinsic Neuronal Excitability in Neurons of the Dorsal Lateral Geniculate Nucleus
05:01

Inducing Long-Term Plasticity of Intrinsic Neuronal Excitability in Neurons of the Dorsal Lateral Geniculate Nucleus

Published on: September 20, 2024

729

Relation between gamma oscillations and neuronal plasticity in the visual cortex.

Ralf A W Galuske1,2, Matthias H J Munk2,3, Wolf Singer1,4,5

  • 1Department of Neurophysiology, Max Planck Institute for Brain Research, 60528 Frankfurt am Main Germany; galuske@bio.tu-darmstadt.de wolf.singer@brain.mpg.de.

Proceedings of the National Academy of Sciences of the United States of America
|October 30, 2019
PubMed
Summary
This summary is machine-generated.

Synchronized gamma oscillations gate long-term neuronal plasticity in the visual cortex. Strong gamma oscillations enhance orientation selectivity, while weak oscillations decrease it, demonstrating network dynamics control neural modifications.

Keywords:
gamma oscillationsneuronal plasticityorientation mapsunsupervised learningvisual cortex

More Related Videos

Generation of Local CA1 γ Oscillations by Tetanic Stimulation
08:02

Generation of Local CA1 γ Oscillations by Tetanic Stimulation

Published on: August 14, 2015

9.4K
Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex
08:42

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex

Published on: February 8, 2020

11.1K

Related Experiment Videos

Last Updated: Jan 5, 2026

Inducing Long-Term Plasticity of Intrinsic Neuronal Excitability in Neurons of the Dorsal Lateral Geniculate Nucleus
05:01

Inducing Long-Term Plasticity of Intrinsic Neuronal Excitability in Neurons of the Dorsal Lateral Geniculate Nucleus

Published on: September 20, 2024

729
Generation of Local CA1 γ Oscillations by Tetanic Stimulation
08:02

Generation of Local CA1 γ Oscillations by Tetanic Stimulation

Published on: August 14, 2015

9.4K
Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex
08:42

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex

Published on: February 8, 2020

11.1K

Area of Science:

  • Neuroscience
  • Computational Neuroscience
  • Systems Neuroscience

Background:

  • Use-dependent plasticity allows neurons to modify their response properties.
  • Gating mechanisms are crucial to prevent irrelevant neural activity from inducing inappropriate modifications.
  • Local network dynamics, particularly synchronized oscillations, may play a role in gating synaptic plasticity.

Purpose of the Study:

  • To investigate the role of synchronized gamma (ɣ) oscillations in gating use-dependent, long-term changes in neuronal response properties.
  • To test the hypothesis that local network dynamics, specifically gamma oscillations, contribute to gating synaptic modifications in the visual cortex.
  • To examine how gamma oscillations influence the modification of orientation selectivity in the adult cat visual cortex.

Main Methods:

  • Examined the effect of synchronized gamma (ɣ) oscillations on stimulation-dependent modifications of orientation selectivity.
  • Induced changes in orientation maps by pairing visual stimulation with electrical activation of the mesencephalic reticular formation.
  • Assessed changes in orientation selectivity using optical recording of intrinsic signals and multiunit recordings.

Main Results:

  • Strong gamma oscillations during conditioning led to expansion of orientation domains matching the stimulus, with neurons shifting preference towards the conditioned orientation.
  • Weak or absent gamma oscillations resulted in decreased responsiveness of neurons to the conditioning stimulus.
  • The observed effects were dependent on the power of low gamma-band oscillations (20-48 Hz) and not on neuronal discharge rates.

Conclusions:

  • The occurrence and polarity of use-dependent long-term changes in cortical response properties are dependent on the presence of gamma oscillations during induction.
  • Gamma oscillations, by influencing temporal coherence of network activity, appear to act as a gating mechanism for synaptic plasticity.
  • These findings highlight the critical role of network-level oscillatory dynamics in regulating experience-dependent cortical plasticity.