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Left ventricular function outcome after coronary artery bypass grafting, King Abdullah Medical City (KAMC)-

Sheeren Khaled1,2, Ehab Kasem3,4, Ahmed Fadel3,5

  • 1Banha University, Benha, Egypt. sheeren.khaled@gmail.com.

The Egyptian Heart Journal : (EHJ) : Official Bulletin of the Egyptian Society of Cardiology
|October 30, 2019
PubMed

Insights

Coronary artery bypass grafting (CABG) significantly improves left ventricle systolic function in patients with low ejection fraction. Diabetes mellitus, diastolic dysfunction, and intra-aortic balloon pump (IABP) insertion predict in-hospital mortality after cardiac surgery.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Cardiovascular Research

Background:

  • Coronary artery bypass grafting (CABG) is a key treatment for ischemic heart disease, particularly in patients with reduced left ventricular (LV) ejection fraction.
  • Understanding the impact of CABG on LV systolic function and identifying predictors of poor outcomes is crucial for patient management.

Purpose of the Study:

  • To evaluate the effect of CABG on left ventricle (LV) systolic function in patients with low ejection fraction.
  • To identify predictors associated with adverse postoperative outcomes following CABG.

Main Methods:

  • A prospective, cross-sectional study included 110 patients with LV ejection fraction (LVEF) < 50% undergoing CABG.
  • Patients were stratified into two groups based on LVEF: >35% (Group I) and <35% (Group II).
  • Demographic, clinical data, and postoperative outcomes were analyzed.

Main Results:

  • A significant improvement in LVEF was observed post-CABG in both groups (p = 0.05).
  • Group II patients exhibited a higher prevalence of diabetes mellitus (DM) and Euro SCORE II compared to Group I.
  • Diabetes mellitus, significant diastolic dysfunction, and intra-aortic balloon pump (IABP) insertion were identified as predictors of in-hospital mortality (p = 0.001, 0.03, and < 0.001, respectively).

Conclusions:

  • CABG leads to significant improvement in LV systolic function and enhances survival rates in patients with low ejection fraction.
  • Diabetes mellitus, significant diastolic dysfunction, and perioperative IABP insertion are critical predictors of mortality after cardiac surgery.
  • Targeted interventions and specialized care for high-risk patients are recommended to improve surgical outcomes.
Abstract

Keywords:
CABGLeft ventricular systolic dysfunctionRisk predictors

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