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Epigenetic Regulation01:46

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Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
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Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
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Gene-Environment Interactions01:20

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Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
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The histone proteins have a flexible N-terminal tail extending out from the nucleosome. These histone tails are often subjected to post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination. Particular combinations of these modifications form “histone codes” that influence the chromatin folding and tissue-specific gene expression.
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Epigenetics in the public sphere: interdisciplinary perspectives.

Michel Dubois1,2, Séverine Louvel3, Anne Le Goff4,5

  • 1Epigenetics, Data, Politics (EpiDaPo), CNRS, The George Washington University, Washington, DC, USA.

Environmental Epigenetics
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Summary

Public interest in epigenetics (epigenetics) is high, but its circulation often involves misconceptions. This study analyzes everyday epigenetics, revealing an

Keywords:
beliefconsumerismempowermentepigeneticsinterdisciplinarityknowledge claimlifestylepublic perceptionscientific culturescientific popularization

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Area of Science:

  • Epigenetics and its public perception.
  • Sociology of science.
  • Science communication.

Background:

  • Public interest in epigenetics is significant, yet empirical research on its societal circulation is limited.
  • Understanding public appropriation of epigenetics is crucial for bridging science and society.
  • Existing research often overlooks the specific forms and drivers of public engagement with epigenetics.

Purpose of the Study:

  • To investigate the modes, reasons, and consequences of epigenetics' public circulation.
  • To analyze the accuracy of public knowledge claims regarding everyday epigenetics.
  • To foster interdisciplinary dialogue between public understanding and scientific knowledge of epigenetics.

Main Methods:

  • Creation of an original database focused on 'lifestyle' or 'everyday' epigenetics.
  • Analysis of public discourse and knowledge claims surrounding epigenetics.
  • Assessment of the accuracy of public epigenetics knowledge against the current scientific state of the art.

Main Results:

  • Epigenetics' social diffusion often incorporates misconceptions about genetics and epigenetics.
  • Public engagement with epigenetics fosters an 'illusion' of control, driving market expansion.
  • A 'scientifization' of cultural epigenetics appropriation indicates an emerging scientific culture.

Conclusions:

  • Public understanding of epigenetics is frequently shaped by beliefs and misconceptions.
  • The popularization of epigenetics can lead to market opportunities based on perceived control.
  • The study highlights the need for effective science outreach to address public epigenetics representations.