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Human iPSC banking: barriers and opportunities

Ching-Ying Huang1, Chun-Lin Liu1, Chien-Yu Ting1

  • 1Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.

Journal of Biomedical Science
|October 30, 2019
PubMed

The introduction of induced pluripotent stem cells (iPSCs) has opened up the potential for personalized cell therapies and ushered in new opportunities for regenerative medicine, disease modeling, iPSC-based drug discovery and toxicity assessment. Over the past 10 years, several initiatives have been established that aim to collect and generate a large amount of human iPSCs for scientific research purposes. In this review, we compare the construction and operation strategy of some iPSC banks as well as their ongoing development. We also introduce the technical challenges and offer future perspectives pertaining to the establishment and management of iPSC banks.

Keywords:
Cell bankInduced pluripotent stem cell (iPSC)Personalized medicine

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