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Updated: Jan 4, 2026
Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants
Published on: March 6, 2018
Neuropsychological effects among workers exposed to organic solvents
Cuauhtémoc Arturo Juárez-Pérez1, Guadalupe Aguilar-Madrid2, Jorge Sandoval-Ocaña3
1Unidad de Investigación de Salud en el Trabajo, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social. Mexico City, Mexico.
Objective:
To assess neuropsychological performance among workers at a paint factory in Mexico City.
Materials And Methods:
During 2004 and 2005 we assessed the neuropsychological performance of 208 workers who were exposed to organic solvents at a paint factory, mainly toluene and xylene. We categorized workers into low and high exposure groups using a cumulative index for toluene, based on times spent in different tasks. We evaluated cognitive and motor functions with 13 neuropsychological tests.
Results:
We found lower attention, longer time to complete the test β=5.5 (R2=12.3%), and a lower score in the motor-cognitive test β=-15.7 (R2=19.5%) in the high exposure group through multiple linear regression model analysis, with adjustment for age and education.
Conclusions:
Our results are similar to the ones reported in the literature, but the effects are less severe, probably due to lower exposure to organic solvents.
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