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Axillary Dissection vs. no Axillary Dissection in Breast Cancer Patients With Positive Sentinel Lymph Node: A Single
Riccardo Arisio1, Fulvio Borella2, Mauro Porpiglia2,3
1Department of Surgical Sciences, Sant'Anna Hospital, Turin, Italy.
Background/Aim:
Axillary surgery of breast cancer patients is undergoing a paradigm shift, as axillary lymph node dissection's (ALND) usefulness is being questioned in the treatment of patients with tumor-positive sentinel lymph node biopsy (SLNB). The aim of this study was to investigate the overall survival (OS) and relapse-free survival (RFS) of patients with positive SLNB treated with ALND or not.
Patients And Methods:
We investigated 617 consecutive patients with cN0 operable breast cancer with positive SLNB undergoing mastectomy or conservative surgery. A total of 406 patients underwent ALND and 211 were managed expectantly.
Results:
No significant difference in OS and RFS was found between the two groups. The incidence of loco-regional recurrence in the SLNB-only group and the ALND group was low and not significant.
Conclusion:
The type of breast cancer surgery and the omission of ALND does not improve OS or RSF rate in cases with metastatic SLN.
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