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A Preclinical Model to Assess Brain Recovery After Acute Stroke in Rats
Published on: November 6, 2019
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Functional recovery and blood pressure on acute post-stroke setting
Farha Ikramuddin1, Fevziye Ünsal Malas1, Karan Chugh1
1Department of Physical Medicine and Rehabilitation, The Minnesota University Medical School, Minnesota, USA.
Turkish Journal of Physical Medicine and Rehabilitation
|October 31, 2019
Summary
Diastolic blood pressure (BP) in subacute stroke patients did not significantly impact functional recovery or hospital length of stay (LOS). However, diastolic BP showed correlations with functional independence measure (FIM) efficiency.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Cardiovascular Science
Background:
- Stroke rehabilitation requires understanding factors influencing patient outcomes.
- Blood pressure (BP) management is crucial in post-stroke care.
- The relationship between BP and functional recovery in the subacute phase needs further elucidation.
Purpose of the Study:
- To evaluate the impact of blood pressure (BP) on functional recovery and length of stay (LOS) in patients with ischemic stroke.
- To analyze the correlation between daily BP measurements and functional outcomes in an acute rehabilitation facility (ARF).
Main Methods:
- 116 ischemic stroke patients admitted to an ARF were included.
- Daily BP, Functional Independent Measure (FIM) scores (admission/discharge), LOS, and BP ranges were recorded.
- Statistical analyses were performed to assess correlations between BP and functional outcomes.
Main Results:
- No significant correlation was found between overall BP and FIM scores.
- Mean diastolic BP positively correlated with admission and discharge FIM scores and FIM effectiveness.
- Diastolic BP negatively correlated with age and LOS, while LOS was negatively correlated with FIM scores.
Conclusions:
- Diastolic blood pressure in the subacute phase of stroke shows no major impact on functional recovery or LOS.
- A significant correlation exists between diastolic BP values and FIM efficiency in stroke survivors.
- Further research may explore optimal BP targets for stroke rehabilitation.
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