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Immunoscintigraphy of ovarian endometriosis. A preliminary study
S H Kennedy1, N D Soper, O A Mojiminiyi
1John Radcliffe Hospital, Headington, Oxford.
British Journal of Obstetrics and Gynaecology
|July 1, 1988
Abstract:
CA-125 is a membrane antigen detected in the serum of some women with gynaecological disease including endometriosis. We attempted to use a radioiodinated anti-CA-125 monoclonal antibody, OC-125, to image ovarian endometriosis using immunoscintigraphy. Two women with significant endometriosis and normal serum CA-125 levels had positive immunoscintigraphy. In one woman, all areas of endometriosis were imaged; in the other, endometriosis in one affected ovary was seen, but uptake in the other ovary was less than the extent of the disease.