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Updated: Aug 4, 2026

In Vivo Mouse Model of Spinal Implant Infection
Published on: June 23, 2020
Micromonas micros: A rare anaerobic cause of late implant failure following spinal surgery
Garret L Sobol1, John I Shin1, Michael J Vives1
1Orthopaedic Surgery, Rutgers New Jersey Medical School, Newark, New Jersey, USA.
Abstract:
Context: Delayed, postoperative, spine infections are rare, most commonly occurring secondary to fastidious, less virulent pathogens. The etiology may involve a distant infectious focus, not related to the index operation. Patients may present months, or even years postoperatively with pain related to mechanical implant failure, often without additional signs of systemic infection.Findings: We present the case of a 59-year-old male who developed rapid disk degeneration and implant failure seven months following instrumented lumbar fusion surgery. The causal organism was found to be Micromonas micros, an anaerobic bacterium typically located in the oral cavity and associated with periodontal disease. The patient was found to have extensive oral caries, which were presumed to have occurred secondary to poor oral hygiene and his use of fentanyl lozenges for chronic back pain. The patient was treated with revision staged spinal surgery and long-term intravenous antibiotics.Conclusion/clinical relevance: This case highlights an unusual etiology of delayed postoperative spinal implant failure and provides evidence for periodontal disease as a source of hematogenous seeding in postoperative spinal infections. The orthopaedist should also be aware of the potential relationship between poor oral hygiene and the use of high sugar content fentanyl lozenges in treating chronic back pain in these patients.
Insights
Delayed spinal infections can stem from oral bacteria, as seen in a patient with implant failure due to periodontal disease. This highlights the importance of oral hygiene in spinal surgery patients.
Area of Science:
- Spinal surgery
- Infectious disease
- Periodontology
Background:
- Delayed postoperative spinal infections are uncommon, often caused by less virulent pathogens.
- Infections may originate from a distant focus unrelated to the initial surgery.
- Patients can present with mechanical implant failure and pain months or years later.
Observation:
- A 59-year-old male experienced rapid disk degeneration and implant failure 7 months after lumbar fusion.
- The infection was caused by Micromonas micros, an oral anaerobic bacterium.
- The patient had severe oral caries, linked to poor hygiene and fentanyl lozenge use.
Findings:
- Micromonas micros, associated with periodontal disease, was identified as the causative agent.
- Poor oral hygiene and fentanyl lozenge use likely led to oral caries and subsequent bacterial seeding.
- The patient underwent revision surgery and received long-term intravenous antibiotics.
Implications:
- Periodontal disease can be an unusual source of hematogenous seeding leading to delayed postoperative spinal infections.
- Orthopaedists should consider the link between poor oral hygiene, fentanyl lozenge use, and spinal implant complications.
- Maintaining oral health is crucial for patients undergoing spinal surgery, especially those with chronic pain management involving sugar-containing medications.
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