Role of implants surface modification in osseointegration: A systematic review

Area of Science:

• Orthopedic Surgery
• Biomaterials Science
• Tissue Engineering

Background:

• Stable implant fixation is critical for successful orthopedic endoprosthesis surgery.
• Osseointegration (OI) is the key process for cementless implant fixation and bone integration.
• Implant surface properties significantly influence the success of osseointegration.

Purpose of the Study:

• To systematically analyze and review contemporary implant surface modification strategies for enhanced osseointegration.
• To provide a comprehensive overview of materials, techniques, and design factors for orthopedic implants.
• To identify current limitations and future directions in implant surface modification.

Main Methods:

• Systematic literature review and analysis.
• Evaluation of contemporary surface modification techniques for orthopedic implants.
• Analysis of materials used in implant fabrication and porous structure design.

Main Results:

• Detailed examination of the osseointegration process and bone-implant interactions.
• Systematic analysis of various surface modification strategies, including materials and techniques.
• Discussion on the advantages of current surface modification approaches and remaining challenges.

Conclusions:

• Surface modification is a significant area of focus for improving implant osseointegration.
• Further research is needed to overcome existing challenges in implant surface modification.
• This review provides essential information for the improved fabrication and design of orthopedic implants.