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Updated: Jan 4, 2026

Bacterial Cellulose Spheres that Encapsulate Solid Materials
Published on: February 26, 2021
Antimicrobial and wound healing properties of a bacterial cellulose based material containing B. subtilis cells
I S Savitskaya1, D H Shokatayeva1, A S Kistaubayeva1
1Al-Farabi Kazakh National University, Al-Farabi av. 71, Almaty, 050038, Kazakhstan.
Abstract:
A biocomposite composed of bacterial cellulose (BC) gel-film and Bacillus subtilis (BS) cells was obtained and characterized with a view to future biomedical applications. The inclusion of functional ingredient (1010/g viable BS cells) in the composite was carried out by their joint aggregation with the BC gel-film. Immobilized BS cells displayed high antagonistic activity towards causative agents of wound infections such as Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Pseudomonas aeruginosa. Application of the BC/BS-biocomposite for the treatment of excision wounds, performed on laboratory animals, stimulated reparative processes and shortened the healing time. Possible mechanisms of the wound-healing effect of BC/BS gel films are discussed. In this work we claim that the developed BC/BS-material can be positioned as a universal wound coating and sanitary-hygienic product.
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